Effect of l-NAME on MMP2 activity (n = 4–6 per group). A) Representative Western Blot showing the formation of proteolytic activation by occurrence of a 58 kDa band and representative zymogram gels. B) Quantification of the Western blot; left ventricle (LV): One-way ANOVA (p = 0.008) with Student-Newman-Keuls post hoc analysis; *, p < 0.05 vs. C; right ventricle (RV): One-way ANOVA (p = 0.000000017) with Student-Newman-Keuls post hoc analysis; *, p < 0.05 vs. C; C) Quantification of zymogram gels: left ventricle: One-way ANOVA (p = 0.061); right ventricle (RV): One-way ANOVA (p = 0.017) with Student-Newman-Keuls post hoc analysis; *, p < 0.05 vs. C. D) MMP2 expression normalized to control values; LV: One-Way ANOVA (p > 0.05) RV: Kruskal-Wallis-Test p < 0.05; with Bonferroni-Test with correction for multiple testing (LS vs. LT: p = 0.039; LS vs. C: p = 0.010; C, n = 11, l-NAME, n = 13; LS and LT, n = 8 each). Data show means ± SD in black and original data points in red. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)