Figure 7.

Whole body lipid and glucose homeostasis are preserved in chow fed Mpc1^AD−/− mice. (A) Total body weight, (B) inguinal and epididymal adipose depot weights, (C) oral glucose tolerance, (D) HOMA-IR index of insulin resistance, (E - F) fasting and CL316,243-stimulated plasma glycerol (E) and non-esterified fatty acids (F) in male and female Mpc1^AD−/− mice or LoxP^+/+ controls fed a standard chow diet. ∗P < 0.05 for MPC^AD−/− vs LoxP^+/+; ^^^P < 0.001 for female vs male. Data are mean ± SE for 8-10 mice per group.