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Total adiposity is maintained in Mpc1AD−/− mice fed a lipid restricted diet. (A, D) Percentage body weight gain, (B, E) total fat and lean mass, and (C, F) incremental oral glucose tolerance for male and female MPCAD−/− mice or LoxP+/+ controls fed either a zero fat, sucrose enriched diet (A–C) or a high fat western-style diet (D–F) for 24 weeks. ∗P < 0.05 for MPCAD−/− vs LoxP+/+. Data are mean ± SE for 8-10 mice per group.
