Table 1.

Characterization of CFIR domains and sub-domains and their applicable semi-structured interview guide prompts and emergent themes.

CFIR domain	CFIR sub-domain(s)	Example of interview guide question/prompt	Related themes
Intervention characteristics	Design; adaptability	Our project focuses specifically on improving PrEP uptake among Black cisgender women. In thinking about our community of focus, what topics should be included in PrEP training for providers? What is available in your clinic? [in reference to new discoveries in PrEP or new medications]	Training content suggestions, particularly those informed by local factors and the FQHCs available resources
Individual characteristics	Knowledge; self-efficacy	We want to know more about how familiar you are with PrEP and what kind of training you’ve had on the topic. Now I want to go over some of the content of the existing provider training. I’m interested in your feedback on how we can adapt the content to best serve clinicians at your site	Training needs of providers as informed by their current knowledge and attitudes regarding PrEP
Outer setting	Patient needs	Next, I’d like to describe some case scenarios and hear your feedback on them. [Are there] scenarios you would like to review that have not been presented?	Training needs of providers as informed by the demographics and perspectives of their FQHCs client population
Inner setting	Climate	We are exploring the option of offering CME or MOC credit. What are your thoughts on this format? What type of ongoing feedback or support do you recommend we provide after the training?	Strategies to optimize uptake and acceptability of training at implementing FQHC as informed by its resources, staff, and climate
Process	Engaging; executing	Who should be trained? How often should training be offered? In thinking about your specific clinic environment, how should the training be offered? (modality, in person versus remote)	Strategies to maximize uptake and impact of training through the implementation process (e.g., identifying training recipients, method of training administration)

PrEP: pre-exposure prophylaxis; FQHC: federally qualified health center; CFIR: Consolidated Framework for Implementation Research; CMR: continuing medical education; MOC: maintenance of certificate.