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Histological spectrum of cutaneous adverse reactions to apalutamide treatment in prostate cancer patients. (A, B) Lichenoid interface dermatitis with a dense dermal-band infiltrate with colloid bodies and without eosinophils. (C, D) Subacute spongiotic dermatitis with marked spongiosis with lymphocytic exocytosis. In the papillary dermis, a mixed infiltrate composed of lymphocytes, neutrophils, and eosinophils could be observed.
