Table 2. Potential metabolic biomarkers identified in LECs of ARC patients.

Lipid name	Class	RT	VIP	P-VALUE	LOG_FOLDCHANGE	Up/Down regulation	AUC
BisMePA(48:5)	BisMePA	11.444	1.535	0.027	−1.359	Down	0.74
Cer(d20:0/16:0)	Cer	11.202	2.644	0.009	−2.873	Down	0.89
Cer(d18:0/18:0)	Cer	11.326	2.940	0.001	3.168	Up	0.94
Cer(d22:1/16:0)	Cer	11.538	2.264	0.042	1.529	Up	0.81
Cer(d22:0/18:0)	Cer	12.857	2.207	0.006	5.736	Up	0.82
DG(18:0/16:0)	DG	10.835	2.088	0.005	−3.471	Down	0.79
DG(18:0/16:0)	DG	10.831	1.785	0.011	−2.175	Down	0.8
DG(18:0/16:0)	DG	11.08	2.94	0.000	2.381	Up	0.92
DG(36:2e)	DG	13.114	2.093	0.004	4.144	Up	0.81
Hex1Cer(d39:3)	Hex1Cer	10.915	2.122	0.002	0.821	Up	0.91
Hex2Cer(d13:0/19:1)	Hex2Cer	11.201	1.760	0.049	2.308	Up	0.67
MePC(35:3)	MePC	10.416	1.670	0.036	1.703	Up	0.79
PC(20:4e/18:0)	PC	11.89	1.607	0.025	2.285	Up	0.82
PC(16:0/22:6)	PC	10.405	1.112	0.020	1.800	Up	0.78
PC(18:0/22:6)	PC	11.213	1.868	0.049	1.803	Up	0.75
PE(40:2)	PE	11.908	2.574	0.000	0.623	Up	0.93
PG(18:0/9:0)	PG	9.016	2.126	0.032	−1.066	Down	0.79
TG(12:0e/6:0/16:0)	TG	10.826	2.432	0.004	−2.830	Down	0.87
TG(12:0e/6:0/16:0)	TG	10.834	1.735	0.022	−2.762	Down	0.7
TG(12:0e/6:0/16:0)	TG	11.105	3.024	0.000	2.614	Up	0.92
TG(20:3e/6:0/11:1)	TG	12.917	1.896	0.008	−2.001	Down	0.76
TG(16:1/14:0/24:0)	TG	12.051	1.906	0.021	0.957	Up	0.76
TG(16:0/18:1/22:0)	TG	12.238	2.147	0.035	2.215	Up	0.79
TG(16:1/20:5/20:5)	TG	11.747	2.397	0.010	−1.274	Down	0.83
WE(13:0/21:2)	WE	11.446	2.735	0.003	5.749	Up	0.94
PE(18:0/20:4)	PE	11.669	1.593	0.038	2.648	Up	0.71