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[Preprint]. 2024 Aug 26:2024.08.26.609768. [Version 1] doi: 10.1101/2024.08.26.609768

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Figure 5. — Motor protein activity is impaired in the neurites of HNRNPA2B1 knockout cells and accelerated in cells expressing RGG mutant HNRNPA2B1. (A) Kymographs of lysosome movement in the neurites of HNRNPA2B1 knockout (left), wildtype rescue (middle) and RGG mutant rescue (right) cells. (B) Quantification of lysosome trafficking speed. The number of cells assayed in each condition is specified. (C) Quantification of lysosome trafficking distance. The number of cells assayed in each condition is specified. P-values were calculated using a Wilcoxon ranksum test.