Figure 5. Pathway analysis of the differentially expressed genes between the protected versus the infected animals in 3 different sample types (samples were taken before SIVmac251 challenges).

O samples: original PBMCs without any stimulation; P samples: PBMCs incubated/stimulated with SIVmac251 virus for 18 hours; M samples: enriched myeloid cells incubated/stimulated with SIVmac251 virus for 18 hours. The protected animals, from the SHIV-vaccinated group, were protected against later SIVmac251 infection, while the infected animals, 3 from the SHIV-vaccinated group and 3 from the naive group, were infected later after SIVmac251 challenges.