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[Preprint]. 2024 Aug 31:2024.08.30.610540. [Version 1] doi: 10.1101/2024.08.30.610540

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Figure 7. — A. Comparison of the impact of chronic sEH inhibition on CBF autoregulation in TPPU-treated versus vehicle-treated DM-ADRD and Sprague Dawley (SD) rats. B. Comparison of the impact of chronic sEH inhibition on CBF autoregulation in TPPU-treated versus vehicle-treated AD and F344 rats. The rats were treated with a vehicle (1% PEG-400 in drinking water) or the sEH inhibitor TPPU (1 mg/kg/day) for 9 weeks. Mean values ± SEM are presented, with 4–10 rats per group. * denotes p < 0.05 for comparisons between the corresponding values in AD rats compared to F344 rats. † denotes p < 0.05 for comparisons between the corresponding values obtained from TPPU-treated rats and vehicle-treated rats within the same strain.