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GIST, DDLPS, UPS and CHS lose APM in high-grade areas. We computed the contrast with the high-infiltrate areas. In fact, the latter are defined as those areas with high lymphocytic infiltrate, therefore where APM function is somehow preserved. The densities of the contrast show that almost all the probability mass fall below 0, indicating a substantial decrease in the probability of having that peculiar APM protein in that specific histotype
