Table 3.
Non-SACTs related to ADR occurrences
| Class of drug | Drugs | N (%) | ADRs | N(%) |
|---|---|---|---|---|
| Antimicrobials | Piperacillin | 15 (10) | Peripheral Neuropathy | 48 (27.4) |
| Ceftriaxone | 4 (2.8) | |||
| Levofloxacin | 10 (12.3) | |||
| Meropenem | 7 (5) | |||
| Anticonvulsants | Pregabalin | 9 (11.1) | ||
| Gabapentin | 1 (1.2) | |||
| Levetiracetam | 2 (2.5) | |||
| Phenytoin | 1 (1.2) | |||
| Psychotropic | Olanzapine | 13 (16) | ||
| Clobazam | 1 (1.2) | |||
| Antiemetic | Ondansetron | 57 (70.4) |
Nausea Vomiting Diarrhea |
8 (4.5) 25 (14.2) 10 (5.7) |
| Opioids | Tramadol | 54 (66.7) | ||
| Opioids | Tramadol | 54 (66.7) |
Nausea Vomiting Tachycardia Lethargy Blurred vision Dizziness |
5 (2.8) 20 (11.4) 1 (0.3) 28 (16) 1 (0.3) 1 (0.3) |
| Morphine | 6 (7.4) | |||
| Anticonvulsants | Gabapentin | 1 (1.2) | ||
| Levetiracetam | 2 (2.5) | |||
| Antimicrobials | Piperacillin | 15 (10) | Febrile neutropenia | 10(5.7) |
| Ceftriaxone | 4 (2.8) | |||
| Levofloxacin | 10 (12.30) | |||
| Meropenem | 7 (5) | |||
| Anticoagulant | Rivaroxaban | 5 (6.2) | Gum bleeding | 2 (1.1) |
| Laxative | Lactulose | 36 (44.4) |
Nausea Fatigue Muscle weakness Tingling sensation |
5 (2.8) 7 (4) 2 (1.1) 5 (2.8) |
| Antiepileptic drugs (AEDs) | Gabapentin | 1 (1.2) |
Fatigue Fatigue grade 1 Fatigue grade 2 Fatigue grade 3 |
16 (5.3) 8 (4.5) 7 (4) 1 (0.3) |
| Levetiracetam | 2 (2.5) | |||
| Pregabalin | 9 (11.1) | |||
| Phenytoin | 1 (1.2) | |||
| Antimicrobials | Piperacillin | 15 (10) |
Fever High grade fever |
10 (5.7) 8 (4.5) |
| Ceftriaxone | 4 (2.8) | |||
| Meropenem | 7 (5) | |||
| Anticonvulsants | Levetiracetam | 2 (2.5) | ||
| Pregabalin | 9 (11.1) | |||
| Corticosteroids | Dexamethasone | 6 (7.40) | Acute gastritis | 5 (2.8) |
| Prednisolone | 6 (7.4) | |||
| NSAIDs | Aspirin | 6 (7.4) | ||
| Antimicrobials | Levofloxacin | 10 (12.3) | Epigastric burning sensation | 2 (1.1) |
| Laxative | Lactulose | 36 (44.4) | ||
| Opioids | Morphine | 6 (7.4) | Constipation | 5 (2.8) |
| Tramadol | 54 (66.7) | |||
| Antiemetic | Ondansetron | 57 (70.4) | Dysphagia | 4 (2.2) |
| Diuretic | Furosemide | 2 (2.5) | ||
| Antimicrobials | Trimethoprim-sulfamethoxazole | 2 (2.5) | Acute liver injury | 1(0.3) |
| NSAIDs | Aspirin | 6 (7.4) | Transaminitis | 2(1.1) |
| Antifungals | Fluconazole | 4 (4.9) | ||
| Voriconazole | 11(13.6) |