Figure 2. Associations between prenatal tobacco exposure (PTE) and brain structure.

Regions are color coded with respect to the color bars on the immediate right of each panel. (Note the different scales of the color bars.) Red- or blue-shaded regions indicate that those associations had p-values less than .05; regions that have thick borders indicate that those associations also passed FDR correction. Blue-shaded regions reflect thinner cortices (A) or smaller surface areas (B) in those with PTE. Red-shaded regions reflect thicker cortices (A) or larger surface areas (B) in those with PTE. These images were generated in MATLAB using data from the ggseg toolbox in R.⁴² LH = left hemisphere. RH = right hemisphere. SM = total surface area. WBV = whole-brain volume.