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[Preprint]. 2024 Aug 31:2024.08.30.610555. [Version 1] doi: 10.1101/2024.08.30.610555

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Figure 2: — Hormone genes differentially expressed by L. reuteri. DEGs annotated as having hormonal function are shown. The genes are annotated with their function, whether they are secreted, a receptor, or intercellular, and what cluster they belong to as in Supplemental Figure S4. The graph shows the log₂ fold change expression of the gene for the indicated comparison. The bars are colored using the log₁₀ scaled mean GeTMM counts to illustrate how abundantly expressed the gene is. Transparent overlays are used on genes not differentially expressed for the given comparison. Comparisons shown: U6475-ULDM4, L. reuteri 6475 on uninduced HIOs compared to LDM4 media control; I6475-ILDM4, L. reuteri 6475 on induced HIOs compared to LDM4 media control; I17938-ILDM4, L. reuteri 17938 on induced HIOs compared to LDM4 media control; I6475-I17938 L. reuteri 6475 compared to L. reuteri 17938 on induced HIOs; ILDM4-ULDM4, LDM4 media control on induced versus uninduced HIOs; I6475-U6475, L. reuteri 6475 on induced versus uninduced HIOs. For each, positive fold changes indicate genes upregulated by the condition listed first.