Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

[Preprint]. 2024 Aug 30:2024.08.30.610426. [Version 1] doi: 10.1101/2024.08.30.610426

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which allows reusers to copy and distribute the material in any medium or format in unadapted form only, for noncommercial purposes only, and only so long as attribution is given to the creator.

PMC Copyright notice

Extended Data Fig. 5. — a) UMAP plot with the major populations (hepatocytes, cholangiocytes, endothelial cells, macrophages, stellate cells, and mesenchyme) of all nuclei in mZ-HLOs.

b) Distinct expression profile all populations in mZ-HLOs. The size of the circle indicates the percentage of nuclei in each population expressing each gene. The color represents the average expression level for the indicated gene.

c) Heatmap showing scaled mean expression of all genes in each cluster. Top 10 marker genes in each cluster have been added as labels.

d) Expression of known hepatoblast and zonal hepatocyte marker genes in each population.

e) Violin plot for expression of AFP (hepatoblast gene), GSS (interzonal hepatocytes), GHR (pericentral hepatocyte), and GLS2 (periportal hepatocyte).