Table 6.
Patients’ risks |
Total ( n =210) |
Malignant tumor [ n , (%)] |
Univariate RR |
p -value |
95%CI |
Multivariate RR |
p -value |
95%CI |
Obesity |
109 |
72/98 (73.5%) |
2.78 |
0.001 |
1.93–4.00 |
1.34 |
0.001 |
1.29–2.55 |
Mother’s age [years] |
||||||||
≤20 |
24 |
18/98 (18.4%) |
Constant |
Constant |
Constant |
Constant |
Constant |
Constant |
>20–25 |
50 |
17/98 (17.3%) |
0.40 |
0.001 |
0.24–0.63 |
0.72 |
0.100 |
-3.26– -0.94 |
>25–30 |
60 |
15/98 (15.3%) |
0.33 |
0.001 |
0.20–0.54 |
0.69 |
0.393 |
-3.486– -1.182 |
>30–35 |
32 |
18/98 (18.4%) |
0.73 |
0.105 |
0.50–1.06 |
1.14 |
0.660 |
-2.239–0.213 |
>35–40 |
40 |
30/98 (30.6%) |
0.95 |
0.73 |
0.71–1.27 |
1.10 |
0.680 |
-1.468–1.027 |
Breastfeeding ≤5 months |
100 |
72/98 (73.5%) |
3.20 |
0.001 |
2.20–4.63 |
1.11 |
0.001 |
1.578–2.883 |
DSD |
17 |
10/98 (10.2%) |
1.42 |
0.104 |
0.93–2.16 |
0.79 |
0.179 |
-0.356–1.908 |
Stress |
97 |
70/98 (71.4%) |
3.04 |
0.001 |
2.13–4.34 |
1.33 |
0.001 |
1.526–2.824 |
Hormone |
21 |
15/98 (15.3%) |
1.68 |
0.001 |
1.23–2.31 |
1.16 |
0.018 |
1.217–2.345 |
Smoking |
96 |
69/98 (70.4%) |
2.74 |
0.001 |
1.94–3.86 |
1.36 |
0.001 |
1.329–2.594 |
Positive heredo-genetic history |
63 |
47/98 (48.0%) |
2.24 |
0.001 |
1.71–2.92 |
1.10 |
0.001 |
1.154–2.612 |
Abnormal birth weight |
34 |
25/98 (25.5%) |
1.72 |
0.001 |
1.30–2.29 |
1.08 |
0.003 |
1.442–2.104 |
Residence area |
||||||||
Rural |
97 |
59/98 (60.2%) |
1.82 |
0.001 |
1.33–2.49 |
1.00 |
0.001 |
1.559–1.733 |
Urban |
113 |
39/98 (39.8%) |
||||||
Pollution |
100 |
70/98 (71.4%) |
2.98 |
0.001 |
2.08–4.25 |
1.30 |
0.022 |
1.119–1.505 |
Rh positive |
159 |
81 (82.7%) |
1.61 |
0.037 |
1.03–2.51 |
1.11 |
0.860 |
-0.737–0.611 |
No postnatal vitamin D |
47 |
20/98 (20.4%) |
0.80 |
0.751 |
0.25–2.68 |
0.83 |
0.855 |
-0.964–0.430 |
No postnatal vaccination |
42 |
18/98 (18.4%) |
0.86 |
0.470 |
0.58–1.29 |
1.08 |
0.453 |
0.288–1.907 |
Menstrual disorders |
36 |
25/98 (25.5%) |
1.62 |
0.001 |
1.21–2.18 |
1.15 |
0.001 |
1.957–3.339 |
Malformations |
102 |
77/98 (78.6%) |
4.07 |
0.001 |
2.67–6.20 |
1.65 |
0.001 |
1.559–1.733 |
UTI |
85 |
45/98 (45.9%) |
1.35 |
0.049 |
1.00–1.81 |
1.28 |
0.053 |
0.006–1.146 |
CI: Confidence interval; DSD: Disorder of sex development; n: No. of cases; Rh: Rhesus; RR: Relative risk ratio; UTI: Urinary tract infection