REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
anti-tdTomato (1:1000)	Sicgen	Cat#AB8181-200, polyclonal goat, RRID: AB_2722750
anti-Melanopsin N15 (1:10000)	A gift from Iggy Provencio	N/A
anti-Melanopsin N38 (1:1000)	Advanced Targeting Systems	Cat #AB-N39, RRID:AB_1608076
anti-Rbpms (1:500)	Abcam	Cat #ab152101, RRID:AB_2923082
anti-VAChT (1:750)	Synaptic Systems	Cat #139103, RRID:AB_887864
anti-Tbr2/Eomes (1:500)	Abcam	Cat #ab183991, RRID:AB_2721040
anti-Calb2 (1:500)	Abcam	Cat #ab277631, RRID: N/A
anti-V5 (1:2000)	Novus Biological	Cat #NB600-379, RRID: AB_10003214
SMI32 (1:500)	Enzo LifeScience	Cat #ENZ-ABS219, RRID: N/A
anti-GFP (1:1500)	Novus Biological	Cat #NB100-1614, RRID: AB_10001164
anti-Prkcd (1:500)	Abcam	Cat #ab182126, RRID:AB_2892154
Deposited data
Integrated ipRGC scRNA-Seq Seurat Object	This paper	Mendeley: https://doi.org/10.17632/36tpcd3ykb.1
Differentially expressed genes between ipRGC clusters	This paper	Mendeley: https://doi.org/10.17632/36tpcd3ykb.1
Tran et al., 2019 scRNA-Seq of adult RGCs	Tran et al., 201933	https://singlecell.broadinstitute.org/single_cell/study/SCP509/mouse-retinal-ganglion-cell-adult-atlas-and-optic-nerve-crush-time-series
Experimental models: Organisms/strains
Opn4cre(DSO)	This study	N/A
Opn4cre (Opn4tm1(cre)Saha/J)	JAX	#035925
Ai14 (Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/J)	JAX	#007914
Ai9 (Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/J)	JAX	#007909
MORF3 (Gt(ROSA)26Sortm3(CAG-sfGFP∗)Xwy/J)	JAX	#035403
mTmG (Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/J)	JAX	#007676
Software and algorithms
R v4.1.2	https://www.r-project.org/	N/A
Cellpose2.0	Stringer et al., 202174	N/A
Fiji (ImageJ1, v1.53t)	NIH	N/A
MATLAB 2021b	Mathworks	N/A