Sotrovimab, casirivimab/imdevimab, tixagevimab/cilgavimab (neutralizing monoclonal antibodies) |
No associated increased risk of adverse pregnancy outcomes. Data are limited; therefore, no final assessment can be made
63
,
111
,
112
,
113
,
114
,
115
,
116
,
117
.
|
Remdesivir (antiviral medicine) |
WHO and RCOG recommend that it should be avoided in pregnancy. But because of the low rates of adverse events, administering the drug may be considered if the patient shows
signs of clinical deterioration
63
,
111
,
118
,
119
.
|
Tocilizumab (interleukin-6 receptor inhibitor) |
Only limited data available. No indications of teratogenicity or fetotoxicity
63
,
111
,
120
,
121
,
122
,
123
.
|
Molnupiravir (antiviral medicine) |
Should not be prescribed
111
.
|
Nirmatrelvir/ritonavir (Paxlovid, protease inhibitors) |
No data on the use of these medications in pregnancy. Must only be administered if potential benefit is clear
124
,
125
.
|