Table 6.

Biphasic release kinetics of PRG^a during storage at different temperatures

Time (months)	Coefficient of determination (R2)
	5°C		25°C		30°C		40°C
	1st phase	2nd phase	1st phase	2nd phase	1st phase	2nd phase	1st phase	2nd phase
1	0.978±0.01	0.955±0.02	0.927±0.01	0.988±0.01	0.956±0.01	0.984±0.01	0.953±0.01	0.999±0.00
2	0.973±0.01	0.988±0.01	0.962±0.02	1.00±0.00	0.951±0.01	0.885±0.06	0.973±0.01	0.995±0.00
3	0.918±0.02	0.999±0.00	0.950±0.00	0.997±0.00	0.941±0.01	0.998±0.00	0.875±0.02	0.998±0.00
6	0.919±0.01	0.990±0.00	0.950±0.02	0.995±0.00	0.922±0.01	0.990±0.00	0.913±0.02	0.996±0.00
9	0.913±0.02	0.992±0.01	0.901±0.02	1.00±0.00	—	—	—	—
12	0.927±0.01	0.986±0.01	0.916±0.02	0.995±0.00	—	—	—	—

^aPRG: pregabalin. 1^st phase obeys zero order kinetics model, 2^nd phase obeys Higuchi kinetics model.