Table 6.
Multifactorial analysis of OS in patients with resistance to EGFR-TKIs
| Factor | Beta coefficient | Std Err | P Value | HR value | Lower 95% CI | Upper 95% CI |
|---|---|---|---|---|---|---|
| Age | 0.553 | 0.220 | 0.012 | 1.738 | 1.128 | 2.678 |
| PD-L1 TPS expression | 1.012 | 0.277 | <0.001 | 2.750 | 1.599 | 4.730 |
| Treatment plan | -0.612 | 0.222 | 0.006 | 0.542 | 0.351 | 0.839 |
| NLR | 0.605 | 0.268 | 0.024 | 1.832 | 1.084 | 3.094 |
| PLR | 0.852 | 0.305 | 0.005 | 2.343 | 1.290 | 4.258 |
Note: EGFR: Epidermal Growth Factor Receptor, TPS: Tumor Proportion Score, NLR: Neutrophil-to-Lymphocyte Ratio, PLR: Platelet-to-Lymphocyte Ratio, PD-L1: Programmed Death-Ligand 1, TKIs: Tyrosine Kinase Inhibitors, OS: Overall Survival, HR: Hazard Ratio.