Table 4. Comparisons among control group and subtypes of PH.
| Parameters | Control (n=52) | PH (n=94) | P values of Fisher’s LSD comparisons | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Chronic pulmonary disease (n=26) | Left heart disease (n=37) | Unknown reason (n=31) | PANOVA | Control vs. chronic pulmonary disease | Control vs. left heart disease | Control vs. unknown reason | Chronic pulmonary disease vs. left heart disease | Chronic pulmonary disease vs. unknown reason | Left heart disease vs. unknown reason | |||
| Gender | 0.935 | |||||||||||
| Male | 22 (42.31) | 13 (50.00) | 17 (45.95) | 14 (45.16) | ||||||||
| Female | 30 (57.69) | 13 (50.00) | 20 (54.05) | 17 (54.84) | ||||||||
| Age, year | 57.69±13.40 | 70.35±12.53 | 65.59±12.15 | 64.39±12.10 | <0.001 | <0.001 | 0.004 | 0.021 | 0.145 | 0.079 | 0.696 | |
| Anemia | 0.021 | |||||||||||
| Yes | 1 (1.96) | 6 (23.08) | 5 (13.89) | 4 (13.33) | ||||||||
| No | 50 (98.04) | 20 (76.92) | 31 (86.11) | 26 (86.67) | ||||||||
| Heart rate on admission, bpm | 78.23±10.29 | 87.27±17.69 | 87.64±17.95 | 79.11±11.65 | 0.007 | 0.012 | 0.005 | 0.790 | 0.926 | 0.043 | 0.025 | |
| Hb, g/L | 145.67±18.68 | 138.69±34.57 | 139.44±26.71 | 144.27±32.24 | 0.619 | 0.288 | 0.294 | 0.823 | 0.914 | 0.445 | 0.474 | |
| RBC, 1012/L | 4.95±0.52 | 5.38±1.07 | 4.88±0.67 | 5.07±0.98 | 0.069 | 0.023 | 0.678 | 0.509 | 0.013 | 0.136 | 0.328 | |
| HCT, % | 43.43±5.25 | 43.97±9.67 | 42.33±6.87 | 43.95±9.48 | 0.798 | 0.769 | 0.505 | 0.768 | 0.401 | 0.995 | 0.395 | |
| MCV, fL | 87.85±6.72 | 81.66±10.65 | 86.85±7.58 | 87.39±12.19 | 0.034 | 0.005 | 0.612 | 0.827 | 0.027 | 0.021 | 0.815 | |
| MCH, pg | 29.49±2.72 | 25.73±4.89 | 28.56±3.65 | 28.84±5.21 | 0.002 | <0.001 | 0.282 | 0.485 | 0.007 | 0.005 | 0.780 | |
| MCHC, g/L | 334.63±12.47 | 312.85±24.43 | 327.75±18.57 | 328.32±21.12 | <0.001 | <0.001 | 0.090 | 0.149 | 0.002 | 0.003 | 0.903 | |
| RDW-SD, fL | 43.56±3.38 | 51.98±7.08 | 51.28±5.62 | 50.38±6.88 | <0.001 | <0.001 | <0.001 | <0.001 | 0.629 | 0.294 | 0.517 | |
| RDW-CV, % | 13.60±1.39 | 18.48±4.53 | 16.49±2.69 | 16.28±3.46 | <0.001 | <0.001 | <0.001 | <0.001 | 0.010 | 0.007 | 0.776 | |
| PLT, 109/L | 262.49±86.63 | 223.00±86.32 | 221.81±68.19 | 197.29±88.60 | 0.007 | 0.052 | 0.025 | 0.001 | 0.956 | 0.260 | 0.241 | |
| PLT P-LCR, % | 21.41±7.77 | 23.52±7.64 | 25.53±5.08 | 25.16±7.44 | 0.034 | 0.232 | 0.008 | 0.026 | 0.283 | 0.406 | 0.836 | |
| ALP, U/L | 105.64±49.45 | 171.51±134.04 | 140.34±53.09 | 124.00±48.92 | 0.002 | <0.001 | 0.030 | 0.270 | 0.098 | 0.015 | 0.361 | |
| γ-GT, U/L | 48.92±50.37 | 83.85±121.01 | 87.33±92.64 | 67.52±67.43 | 0.127 | 0.077 | 0.032 | 0.318 | 0.869 | 0.452 | 0.323 | |
| TB, μmol/L | 11.92±4.45 | 40.48±58.86 | 24.15±13.28 | 20.98±24.78 | <0.001 | <0.001 | 0.049 | 0.162 | 0.027 | 0.011 | 0.649 | |
| DB, μmol/L | 3.89±1.88 | 31.40±57.09 | 11.62±8.00 | 10.76±15.17 | <0.001 | <0.001 | 0.159 | 0.231 | 0.003 | 0.003 | 0.889 | |
| ALB, g/L | 41.67±3.86 | 37.36±5.36 | 37.51±5.66 | 35.89±4.86 | <0.001 | <0.001 | <0.001 | <0.001 | 0.906 | 0.264 | 0.178 | |
| UA, μmol/L | 297.89±99.70 | 442.48±225.73 | 439.75±133.94 | 377.01±165.71 | <0.001 | <0.001 | <0.001 | 0.024 | 0.945 | 0.107 | 0.094 | |
| GLU, mmol/L | 4.85±1.18 | 4.13±1.25 | 5.11±1.37 | 5.00±1.41 | 0.037 | 0.030 | 0.387 | 0.627 | 0.007 | 0.017 | 0.739 | |
| Cr, μmol/L | 74.31±17.08 | 74.61±18.62 | 95.07±49.48 | 80.39±19.60 | 0.01 | 0.96 | 0.002 | 0.38 | 0.009 | 0.47 | 0.06 | |
| LDL-C, mmol/L | 3.24±1.03 | 2.34±0.87 | 3.05±0.86 | 2.14±0.67 | <0.001 | <0.001 | 0.40 | <0.001 | 0.006 | 0.48 | <0.001 | |
| HDL-C, mmol/L | 1.30±0.31 | 1.06±0.56 | 1.18±0.32 | 0.98±0.31 | 0.01 | 0.02 | 0.22 | 0.003 | 0.26 | 0.48 | 0.07 | |
| TG, mmol/L | 1.30±0.80 | 0.90±0.37 | 0.99±0.57 | 0.97±0.40 | 0.03 | 0.01 | 0.02 | 0.03 | 0.57 | 0.69 | 0.88 | |
Data are presented as mean ± standard deviation or number (percentage). Hb, hemoglobin; RBC, red blood cell; HCT, hematocrit; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; RDW-SD, red blood cell volume distribution width-standard deviation; RDW-CV, red blood cell volume distribution width-coefficient of variation; PLT, platelet; PDW, platelet distribution width; MPV, mean platelet volume; P-LCR, platelet-large cell ratio; PCT, plateletcrit; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase; γ-GT, γ-glutamyltransferase; TB, total bilirubin; DB, direct bilirubin; IB, indirect bilirubin; ALB, albumin; UA, urine acid; GLU, glucose; Cr, creatinine; LDL-C, low density lipoprotein-cholesterol; HDL-C, high density lipoprotein-cholesterol; TG, triacylglycerol.