Table 2. Treatment response by YAP1 expression.
| Treatment response | YAP1-negative | YAP1-positive | P |
|---|---|---|---|
| Total | n=152 | n=38 | |
| CR | 14 (9.2) | 7 (18.4) | 0.18 |
| PR | 112 (73.7) | 23 (60.5) | |
| SD, PD, or not evaluated | 26 (17.1) | 8 (21.1) | |
| Objective response rate (CR + PR) | 126 (82.9) | 30 (78.9) | 0.57 |
| Limited-stage | n=58 | n=13 | |
| CR | 13 (22.4) | 6 (46.2) | 0.09 |
| PR | 40 (69.0) | 5 (38.5) | |
| SD, PD, or not evaluated | 5 (8.6) | 2 (15.4) | |
| Objective response rate (CR + PR) | 53 (91.4) | 11 (84.6) | 0.60 |
| Extensive-stage | n=94 | n=25 | |
| CR | 1 (1.1) | 1 (4.0) | 0.48 |
| PR | 72 (76.6) | 18 (72.0) | |
| SD, PD, or not evaluated | 21 (22.3) | 6 (24.0) | |
| Objective response rate (CR + PR) | 73 (77.7) | 19 (76.0) | 0.86 |
The variables are presented as number (%). CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease.