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. 2024 Sep 9;14:20930. doi: 10.1038/s41598-024-71419-x

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

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Fig. 4 — Biomarker correlation matrix indicating difference in patter of healthy donors (A), and convalescence in D30 (B), D60 (C) and D90 (D). Networks were based on Spearman’s correlation indices (r). Association was significant when p < 0.05 between all markers analyzed. Blue scale, ranging from − 1.0 to 1.0, shows correlation strength, as represented on image. WBC white blood count, ANC absolute neutrophil count, ALC absolute lymphocyte count, AMC absolute monocyte count, AEC absolute eosinophil count, ABC absolute basophil count, NK natural killer, Chemokines CXCL8, CXCL10, CCL3, CCL4, CCL2, CCL5 and CCL11, Cytokines IL-1β, IL-1ra, IL-6, TNF-α, IL-12p70, IFN-γ, IL-2, IL-7, IL-9, IL-15, IL-4, IL-5, IL-13, IL-17A, IL-10, Growth factors VEGF, FGF basic, PDGF-BB, GM-CSF, G-CSF, HD healthy donors.