Table 2.
Laboratorial parameters of healthy donors and convalescent patients at D30, D60 and D90.
| Variables | HD n = 51 |
D30 n = 62 |
D60 n = 48 |
D90 n = 47 |
p value |
|---|---|---|---|---|---|
| RBC (× 106/µL, median [IQR]) | 4.99 [4.59–5.40] | 4.90 [4.56–5.20] | 4.89 [4.47–5.15] | 4.89 [4.71–5.29] | 0.4676 |
| Hemoglobin (g/dL, median [IQR]) | 14.90 [13.60–16.00] | 14.40 [13.38–15.03] | 14.35 [13.23–14.90] | 14.40 [13.50–15.10] | 0.0602 |
| Hematocrit (%, median [IQR]) | 44.70 [40.6–47.4] | 42.60 [40.45–45.45] | 42.75 [39.13–44.50] | 43.90 [41.50–46.20] | 0.0660 |
| MCV (fL, median [IQR]) | 87.80 [84.70–90.40] | 88.15 [84.85–90.80] | 87.90 [84.35–91.08] | 89.10 [85.30–91.40] | 0.7292 |
| MCH (pg, median [IQR]) | 29.70 [28.8–30.70] | 29.60 [28.38–30.60] | 29.85 [28.10–30.70] | 29.80 [27.90–30.80] | 0.8607 |
| MCHC (g/dL, median [IQR]) | 34.05 [33.10–34.60] | 33.70 [32.78–34.450] | 33.59 [32.75–34.48] | 33.40 [32.60–34.10] | 0.1667 |
| RDW (%, median [IQR]) | 13.70 [13.10–14.00] | 14.40 [13.75–14.95] | 14.40 [13.90–15.08] | 14.35 [13.68–15.03] | < 0.0001a,b,c |
| WBC (× 106/µL, median [IQR]) | 6.33 [5.17–6.95] | 6.78 [5.87–7.51] | 6.34 [5.75–7.57] | 6.65 [5.61–7.97] | 0.2906 |
| Neutrophil (× 103/µL, median [IQR]) | 3.34 [2.8–4.17] | 4.00 [3.21–4.65] | 3.80 [3.14–4.61] | 3.79 [3.04–4.84] | 0.0757 |
| Lymphocyte (× 103/µL, median [IQR]) | 1.85 [1.59–2.18] | 1.98 [1.61–2.22] | 1.93 [1.6–2.3] | 1.98 [1.61–2.23] | 0.8081 |
| Monocyte (× 103/µL, median [IQR]) | 0.38 [0.28–0.42] | 0.43 [0.37–0.48] | 0.37 [0.33–0.42] | 0.38 [0.28–0.43] | 0.0028a,d,e |
| Basophil (× 103/µL, median [IQR]) | 0.03 [0.02–0.05] | 0.04 [0.02–0.06] | 0.03 [0.02–0.04] | 0.03 [0.02–0.05] | 0.2906 |
| Eosinophil (× 103/µL, median [IQR]) | 0.19 [0.12–0.38] | 0.19 [0.13–0.26] | 0.18 [0.13–0.26] | 0.16 [0.12–0.26] | 0.6799 |
| Platelet count (× 103/µL, median [IQR]) | 243.0 [210–282] | 259.5 [212–290] | 245.0 [215–266] | 245.00 [209–272] | 0.7717 |
aSignificant difference for HD vs D30; bSignificant difference for HD vs D60; cSignificant difference for HD vs D90; dSignificant difference for D30 vs D60; eSignificant difference for D30 vs D90; fSignificant difference for D60 vs D90. Statistical analysis was performed with Kruskal–Wallis test, and Dunn’s Multiple Comparison Test to compare hematological values from all groups. A p < 0.05 was considered significant and highlighted by bold type font.