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[Preprint]. 2024 Aug 28:rs.3.rs-4809633. [Version 1] doi: 10.21203/rs.3.rs-4809633/v1

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MALPs are the major source of osteoclast regulatory factors in bone marrow.

(A) UMAP plot of mesenchymal subpopulations in human bone marrow. Bone samples were collected from femoral heads after hip replacement surgery.

(B) Dot plot of TNFSF11, CSF1, THY1 and adipogenic markers in mesenchymal subpopulations.

(C) Fluorescent images of AdipoqER/Td mouse bone marrow stained for Rankl mRNA by RNA FISH. Scale bar=20 μm.

(D) Fluorescent images of bone marrow co-stained for Pparg and Rankl mRNA by RNA FISH. Scale bar=20 μm.

(E) Fluorescent images of AdipoqER/Td mouse bone marrow stained for Csf1 mRNA by RNA FISH. Scale bar=20 μm.