Table 2. Significant effect of hypermethylation level of RARs on prognosis in STAD.

CpG	HR	95% CI	P value
RARA-Body-Open_Sea-cg02477677	0.522	0.341–0.798	0.001
RARA-TSS200-Open_Sea-cg09858022	0.610	0.411–0.907	0.01
RARA-5'UTR- N_Shore-cg00442282	1.515	1.072–2.141	0.02
RARA-TSS200-Open_Sea-cg03053374	0.677	0.483–0.949	0.02
RARA-Body-Island-cg11522012	1.416	1.025–1.957	0.03
RARA-Body-Open_Sea-cg11316510	0.707	0.509–0.982	0.04
RARA-Body-S_Shore-cg10062919	1.542	1.022–2.325	0.03
RARA-TSS200-Open_Sea-cg22935450	0.717	0.520–0.989	0.04
RARA-Body-Island-cg08446900	1.492	1.000–2.226	0.04
RARB-TSS1500-Open_Sea-cg00371702	0.607	0.430–0.858	0.006
RARB-5'UTR;1stExon-Open_Sea-cg19003815	0.585	0.399–0.858	0.004
RARB-TSS1500-Open_Sea-cg18094781	0.584	0.384–0.886	0.008
RARB-5'UTR;Body-Open_Sea-cg01794805	1.723	1.127–2.633	0.008
RARB-5'UTR;1stExon-Open_Sea-cg03428864	0.580	0.377–0.893	0.009
RARB-5'UTR;1stExon-Open_Sea-cg27486427	0.594	0.387–0.914	0.01
RARB-TSS200-Open_Sea-cg06720425	0.670	0.472–0.949	0.03
RARB-TSS1500-Open_Sea-cg26124016	0.620	0.403–0.953	0.02
RARB-TSS1500-Open_Sea-cg20899354	0.634	0.412–0.975	0.03
RARG-Body-N_Shelf-cg21746001	0.617	0.445–0.854	0.004
RARG-1stExon;5'UTR;Body-Island-cg15260268	0.699	0.505–0.969	0.03
RARG-Body-Open_Sea-cg27036638	0.653	0.435–0.980	0.04
RARG-TSS1500-S_Shore-cg12820608	1.540	1.009–2.351	0.046
RARG-Body-N_Shore-cg13937905	0.658	0.436–0.992	0.046

CI, confidence interval; HR, hazard rate; RARs, retinoic acid receptors; STAD, stomach adenocarcinoma.