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. 2024 Sep 10;9(17):e179291. doi: 10.1172/jci.insight.179291

Figure 10. Hypercholesterolemia alters the expression of sncRNA biogenesis–related genes in cauda epididymis.

Figure 10

(A) Schematic of the testis and epididymis. Sperm generated in the testis undergo maturational changes during transiting through the caput and cauda epididymis. (B–D) Three-week-old male LDLR–/– mice were fed an LCD or HCD for 9 weeks. Total RNAs were isolated from the testis (B), and caput (C), and cauda (D) epididymis. The expression levels of indicated genes related to sncRNA biogenesis were analyzed by qPCR (n = 3, *P < 0.05, **P < 0.01, 2-sample, 2-tailed Student’s t test). All data are plotted as mean ± SEM.