Table 2.

Results from linear regression analysis of the relationship between levels of inflammatory cytokines and active/sham stimulation.

	Model 1: No adjustments		Model 2: Demographic adjustments		Model 3: Adjustment for autonomic neuropathy		Model 4: Adjustment for inflammatory level
	Coefficient (95% CI)	p-value	Coefficient (95% CI)	p-value	Coefficient (95% CI)	p-value	Coefficient (95% CI)	p-value
Study period 1
IL-6	0.19 (− 0.81–1.19)	0.71	0.27 (− 0.78–1.32)	0.61	0.49 (− 0.54–1.52)	0.35	− 0.03 (− 0.90–0.83)	0.94
IL-8	− 0.97 (− 2.05–0.11)	0.08	− 1.02 (− 2.13–0.09)	0.07	− 0.77 (− 1.20–0.45)	0.21	− 0.21 (− 1.12–0.70)	0.65
IL-10	− 0.01 (− 0.06–0.05)	0.76	− 0.01 (− 0.06–0.05)	0.76	0.01 (− 0.05–0.06)	0.84	0.00 − 0.05–0.06)	0.87
TNF-α	− 0.07 (− 0.18–0.04)	0.21	− 0.07 (− 0.19–0.04)	0.21	− 0.09 (− 0.22–0.03)	0.14	− 0.09 (− 0.22–0.03)	0.15
IFN-γ	− 0.32 (− 8.26–7.61)	0.94	− 1.73 (− 10.06–6.59)	0.68	− 0.91 (− 10.01–8.19)	0.84	0.53 (− 8.31–9.37)	0.91
Study period 2
IL-6	− 0.23 (− 0.70–0.25)	0.34	− 0.21 (− 0.71–0.29)	0.40	− 0.22 (− 0.75–0.31)	0.42	− 0.31 (− 0.83–0.21)	0.24
IL-8	− 0.28 (− 1.62–1.06)	0.68	− 0.43 (− 1.82–0.97)	0.54	− 0.07 (− 1.32–1.19)	0.92	0.04 (− 1.10–1.18)	0.94
IL-10	0.04 (− 0.04–0.12)	0.35	0.04 (− 0.05–0.13)	0.36	0.02 (− 0.06–0.11)	0.58	0.02 (− 0.07–0.10)	0.70
TNF-α	0.04 (− 0.20–0.28)	0.74	0.04 (− 0.20–0.29)	0.72	0.12 (− 0.15–0.38)	0.39	0.02 (− 0.20–0.25)	0.83
IFN-γ	13.53 (− 18.71–45.76)	0.41	17.93 (− 15.62–51.47)	0.29	21.66 (− 14.93–28.25)	0.24	− 3.42 (− 14.40–7.56)	0.54