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. 2024 Sep 9;14:20980. doi: 10.1038/s41598-024-72027-5

Table 2.

The relationships between NLR and mortality in cancer participants.

Mortality NLR Lower NLR (n = 3138) Higher NLR (n = 1836)
HR 95% CI P value HR HR 95% CI P value
All-cause mortality
 Unadjusted 1.21 1.15–1.25  < 0.001 Ref 2.02 1.73–2.36  < 0.001
 Model 1 1.11 1.07–1.14  < 0.001 Ref 1.44 1.27–1.63  < 0.001
 Model 2 1.10 1.07–1.13  < 0.001 Ref 1.38 1.22–1.55  < 0.001
Cardiovascular mortality
 Unadjusted 1.23 1.16–1.31  < 0.001 Ref 2.72 2.11–3.52  < 0.001
 Model 1 1.14 1.08–1.21  < 0.001 Ref 1.74 1.36–2.22  < 0.001
 Model 2 1.12 1.06–1.18  < 0.001 Ref 1.63 1.27–2.09  < 0.001
Cancer-specific mortality
 Unadjusted 1.15 1.09–1.21  < 0.001 Ref 1.92 1.54–2.41  < 0.001
 Model 1 1.07 1.01–1.12 0.014 Ref 1.48 1.19–1.86  < 0.001
 Model 2 1.06 1.01–1.12 0.023 Ref 1.45 1.17–1.79  < 0.001

Survey sample weights were taken into consideration in the Cox models accompanying the NHANES data. Model 1 was adjusted for gender, age, race, marital status, educational level, family income level, smoke history. Model 2 was additionally adjusted for the presence of comorbidities such as DM, CHD, HF, HBP, high cholesterol, stroke, chronic bronchitis and liver diseases.

HF heart failure, CHD coronary heart disease, HBP hypertension, DM Diabetes.