Table 2.
Health-related quality of life, psychological distress and health anxiety following diagnosis of unruptured intracranial aneurysm.
| Cases |
Control1 |
Regression coefficient (95% CI)a | Control2 |
Regression coefficient (95% CI)a | ||||
|---|---|---|---|---|---|---|---|---|
| Baseline | Follow-up | Baseline | Follow-up | Baseline | Follow-up | |||
| EQ-5D-5L | ||||||||
| EQ-Index, median (IQR) | 0.937 (0.121) | 0.937 (0.077) | 0.937 (0.117) | 0.937 (0.140) | −0.008 (−0.032, 0.016) | 0.937 (0.082) | 0.937 (0.140) | −0.0004 (−0.029, 0.028) |
| Missing EQ-Index, n (%) | 5 (6.6) | 5 (6.6) | 4 (2.6) | 4 (2.6) | 9 (6.5) | 9 (6.5) | ||
| EQ VAS, median (IQR) | 80.0 (17.5) | 80.0 (20) | 80.0 (20.0) | 80.0 (15.0) | −3.87 (−7.60, −0.14) | 80.0 (20.0) | 82.5 (20.0) | −3.02 (−7.61, 1.57) |
| Missing EQ VAS, n(%) | 4 (5.3) | 4 (5.3) | 6 (3.9) | 6 (3.9) | 11 (7.9) | 11 (7.9) | ||
| Hopkins Symptom Checklist-10 | ||||||||
| Sum score, median (IQR) | 1.20 (0.40) | 1.20 (0.40) | 1.10 (0.40) | 1.10 (0.30) | 0.061 (−0.019, 0.14) | 1.15 (0.40) | 1.10 (0.40) | 0.061 (−0.020, 0.14) |
| Above cut-off, n/total (%) | 3/66 (4.6) | 6/66 (9.1) | 8/141 (5.7) | 9/141 (6.4) | 0.52 (−0.64, 1.68) | 11/126 (8.7) | 7/126 (5.6) | 1.21 (−0.24, 2.66) |
| Missing, n (%) | 10 (13.2) | 10 (13.2) | 11 (7.2) | 11 (7.2) | 13 (9.4) | 13 (9.4) | ||
| Whitley Index-6 | ||||||||
| Sum score, median (IQR) | 2 (3.0) | 3 (4.5) | 2 (4.0) | 2 (4.0) | 0.56 (−0.15, 1.27) | 2 (5.0) | 3 (6.0) | 0.27 (−0.57, 1.12) |
| Missing, n (%) | 4 (5.3) | 4 (5.3) | 9 (5.9) | 9 (5.9) | 9 (6.5) | 9 (6.5) | ||
CI, confidence interval; IQR, interquartile range.
a
Separate regression analyses of differences between cases and the two control groups at follow-up, adjusted for corresponding baseline values; linear regression for continuous variables and logistic regression for the binary variable (above cut-off). The regression coefficient represents the difference in outcome for the cases compared to the control group.