Table 3.

Body and bladder weight in smTREK-1 KO mice compared with littermate control mice (SM22-Cre^−/−) at 6 mo of age

	Body, g	Bladder, mg	Bladder, %
Females
SM22-Cre−/−::TREK-1fl/fl
Ctrl	24.6 ± 0.9	19.4 ± 3.8	0.09 ± 0.01
SM22-Cre−/−::TREK-1fl/WT
Ctrl	23.4 ± 1.3	15.8 ± 1.4	0.07 ± 0.00
SM22-Cre+/::TREK-1Ex/Ex
smKO	24.6 ± 0.9	16.0 ± 0.7	0.07 ± 0.00
Males
SM22-Cre−/−::TREK-1fl/fl
Ctrl	31.2 ± 0.7	25.4 ± 1.0	0.08 ± 0.00
SM22-Cre−/−::TREK-1fl/WT
Ctrl	31.5 ± 0.5	26.7 ± 0.6	0.08 ± 0.00
SM22-Cre+/::TREK-1Ex/Ex
smKO	33.7 ± 1.6	26.8 ± 0.9	0.08 ± 0.00

Data are presented as means ± SD. Ctrl, control; smKO, smooth muscle-specific (sm)TREK-1 knockout (KO).