Table 3.

A: Distribution of aortic cross-clamp time and cardiopulmonary bypass time according to valve type in the study population overall, and in isolated and combined procedures; data are median (I quartile-III quartile). B: Results of the weighted Gamma models evaluating the association with valve type. Gamma models’ results are reported as Average Marginal Effect (AME) for Magna Ease vs. Intuity and Intuity vs. Inspiris, lower and upper bound of the 95 % Confidence Interval, and p-value.

A
Variables	Intuity (N=1688)	Magna (N=296)	Inspiris (N=605)	Combined (N=2589)
Cardiopulmonary bypass time (CPB) (min)
Isolated SAVR	82.5 [65–101]	110 [95–123]	90 [77.5–111]	87 [68.25–107]
Combined procedure	120 [95–147.5]	168.5 [145–194.25]	130 [104–150]	130 [102–162]
Overall	91 [71–118]	135 [109–175]	107 [86–134]	99.5 [77–130]
Aortic Cross Clamp time (ACC) (min)
Isolated SAVR	55 [45–70]	87 [75–98]	70 [60–85]	60.5 [48–77]
Combined procedure	83 [67–106]	131 [110–149]	101.5 [80–118]	96 [73–122]
Overall	62 [48–81]	105 [85–134]	82 [66–107]	71 [53–95]

B
Device comparison	AME	Lower	Upper	P-value
ME vs Intuity
CPB Isolated	23.37	19.13	27.61	< 0.001
CPB Combined	46.38	38.56	54.19	< 0.001
ACC Isolated	27.44	24.3	30.58	< 0.001
ACC combined	42.85	37.38	48.31	< 0.001
Inspiris vs Intuity
CPB Isolated	3.33	−1.003	7.67	0.132
CPB Combined	7.68	−0.55	15.91	0.067
ACC Isolated	10.56	7.34	13.78	< 0.001
ACC combined	11.18	5.51	16.84	< 0.001

Table legend: CPB: Cardiopulmonary bypass; SAVR: Surgical aortic valve replacement; ACC: Aortic cross-clamp; ME: Magna Ease.