Table 2.
Number of events among SGLT2 inhibitor treated | Number of events among non-SGLT2 inhibitor treated | KM-rate among SGLT2 inhibitor treated | KM-rate among non SGLT2 inhibitor treated | Unadjusted HR (95% CI) | Adjusted HR (95% CI) | |
---|---|---|---|---|---|---|
Composite of first hospitalisation for heart failure or all-cause death | 180 | 1299 | 8.2 | 15.8 | 0.52 (0.45–0.61) | 0.70 (0.59–0.82) |
First hospitalisation for heart failure | 106 | 600 | 5.0 | 7.6 | 0.66 (0.54–0.82) | 0.78 (0.63–0.98) |
All-cause death | 83 | 772 | 4.0 | 9.5 | 0.43 (0.35–0.54) | 0.64 (0.50–0.80) |
Stroke | 25 | 144 | 1.3 | 1.9 | 1.12 (0.63–1.97) | 0.86 (0.54–1.35) |
Adjusted for age, sex, eGFR, BMI, HbA1c-level, smoking status, clinical frailty score, Killip class at admission, MI classification (STEMI/NSTEMI), left ventricular ejection fraction, year of admission, treatment with angiotensin-converting enzyme inhibitors/angiotensin II receptor blockers, beta-blockers, statins, aspirin and insulin, diagnosis of hypertension and COPD, and prior stroke, heart failure, and myocardial infarction.
CI, Confidence interval; HR, Hazard ratio; KM, Kaplan–Meier.