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. 2024 Aug 20;10(17):e36565. doi: 10.1016/j.heliyon.2024.e36565

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© 2024 The Authors

This is an open access article under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Fig. 3 — VM subtypes and characterization of the two subclusters. (A) Cumulative distribution function (CDF) curves in consensus cluster analysis. CDF curves are shown for consensus scores for different numbers of subtypes (k = 2–10). The relative change in the area under the CDF curve for k = 2–10 is also shown. (B) Consensus score matrix for all samples when k = 2–6. (C) Sample distribution of the consensus matrix for k = 2. (D) The t-SNE analysis showed differences in the transcriptome between the two subclusters. (E-G) OS, OS (1-year), and PFI survival analysis of two subclusters. (H) Distribution of different immune subtypes in two subclusters. (I) GSEA enrichment analysis of two subclusters differential genes. (J) Genomic characterization of high-frequency mutant genes in two breast cancer subgroups.