Fig. 5.

Construction and validation of VM risk models. (A) Trajectories for each independent variable and confidence intervals with different lambda values. (B–C) Univariate and multivariate cox analysis of VM prognostic genes. (D–E) Univariate and multivariate cox analysis of VM risk scores and clinical factors. (F) Kaplan-Meier curves of OS and DSS for TCGA-BRCA high and low VMscore subgroups. (G) ROC curves, OS sensitivity and specificity based on VMscore prediction of the training sets for 1, 3 and 5 years. (H) Kaplan-Meier curves of the RFS for the high VMscore and low VMscore subgroups of the validation sets. (I) ROC curves, RFS sensitivity and specificity based on VMscore prediction of the validation sets for 1, 3 and 5 years. (J–K) Risk score for training and validation sets.