Table 3.
Determining the cutoff threshold of the expression of CD71 on neutrophils based on the metastatic spread using the two-tailed minimal p-value approach (chi-square test; n = 70).
| MFI CD71 (%) | p-value (chi-sqare test) | CD71 Expression | N | Probability of metastasis (%) |
|---|---|---|---|---|
| 200 | 0.14 | Low | 5 | 0 |
| High | 65 | 44.4 | ||
| 250 | 0.05 | Low | 14 | 7.1 |
| High | 56 | 34.0 | ||
| 300 | < 0.01 | Low | 26 | 3.8 |
| High | 44 | 43.2 | ||
| 350 | < 0.01 | Low | 35 | 8.6 |
| High | 35 | 48.6 | ||
| 400 | < 0.01 | Low | 42 | 16.7 |
| High | 28 | 46.4 | ||
| 450 | 0.19 | Low | 53 | 24.5 |
| High | 17 | 41.2 | ||
| 500 | 0.26 | Low | 61 | 26.2 |
| High | 9 | 44.4 |
The optimal cutoff value with the lowest p-value and the highest probability of metastatic spread is highlighted in bold.