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. 2024 Sep 10;148(1):40. doi: 10.1007/s00401-024-02800-3

Fig. 3.

Fig. 3

Summary of the clinical and molecular features of DMG-A and DMG-B. DMG-A is enriched for adult patients, medullary localisation and MAPK-associated mutations, and contains more cases with a methylated MGMT promoter. Contrarily, DMG-B is enriched for paediatric patients, pontine localisation and cases with TP53-mutations. The overall survival of patients with DMG-A is superior to that of patients with DMG-B