Fig. 3. Associations between environment and developmental increases in local segregation are enriched in somatomotor systems.
a The heterogenous patterning of the magnitude of age-by-disadvantage associations (F-statistic) with local segregation is shown on the cortical surface. Regions that show significant age-by-disadvantage associations passing FDR correction at pFDR < 0.05 are outlined in black. b Prenatal disadvantage associations with developmental increases in local segregation are enriched in somatomotor systems. Boxplots show the magnitude of age-by-disadvantage associations; each point is an individual parcel (n = 286 parcels, excluding parcels with system assignment None). Boxplots show median and 25–75% interquartile range; whiskers extend to 1.5 * interquartile range, points outside are shown as outliers. c The magnitude of age-by-disadvantage associations is related to a canonical sensorimotor-to-association axis of cortical organization. Each point is an individual parcel, the color of the points represents the magnitude of age-by-disadvantage association. A Spearman’s correlation between these two measures assessed by a conservative two-sided spin-based rotation test was significant (ρ(331) = −0.33, pspin = 0.002, 95% CI = [−0.43, −0.24]). The predicted negative linear relationship between these two measures is plotted with a 95% confidence interval, colors of the points correspond to the magnitude of age-by-disadvantage associations with regional local segregation.