REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Rabbit polyclonal to RAC1	Thermo Fisher Scientific	Cat# PA1-091, RRID:AB_2539856
Rabbit monoclonal to HMOX1 [EP1391Y]	Abcam	Cat# ab52947, RRID:AB_880536
Mouse monoclonal to IRP1	Santa Cruz Biotechnology	Cat# sc-166022, RRID:AB_2273699
Rabbit monoclonal to GAPDH [14C10]	Cell Signaling Technologies	Cat# 2118, RRID:AB_561053
Anti-rabbit IgG, HRP-linked	Cell Signaling Technologies	Cat# 7074, RRID:AB_2099233
Anti-mouse IgG, HRP-linked	Cell Signaling Technologies	Cat# 7076, RRID:AB_330924
Goat anti-Rabbit IgG, Alexa Fluor™ 555	Thermo Fisher Scientific	Cat# A-21429, RRID:AB_2535850
Mouse monoclonal to EPCAM [HEA-125]	Miltenyi Biotec	Cat# 130-113-263, RRID:AB_2726064
Bacterial and virus strains
DH5α chemically competent cells	Thermo Fisher Scientific	Cat#18258012
Biological samples
PA-14-13 Patient-Derived tumor cells	Jing Yang	N/A
Chemicals, peptides, and recombinant proteins
Cobalt (III) Protoporphyrin IX chloride	Enzo Life Sciences	Cat# ALX-430-076-M025
FeCl3	Sigma Aldrich	Cat# 157740
Rotenone	MedChemExpress	Cat# HY-B1756
AP-III-a4	MedChemExpress	Cat# HY-15858
BDP9066	MedChemExpress	Cat# HY-111424A
Y27632	MedChemExpress	HY-10583
IPA-3	MedChemExpress	Cat# HY-15663
EHT 1864	MedChemExpress	Cat# HY-16659
DMSO	Sigma Aldrich	Cat# D2650
DFO	Sigma Aldrich	Cat# D9533
RIPA Buffer	Thermo Fisher Scientific	Cat# 89900
Oxalic Acid	Sigma Aldrich	Cat# 194131-5G
Collagen I	Corning	Cat# CB354249
Trizol	Sigma Aldrich	Cat# 15596026
Critical commercial assays
CellTiter MTS Assay	Promega	Cat# G3582
RPA	Squarix Biotechnology	Cat# ME043.1
Lipofectamine 3000	Thermo Fisher Scientific	Cat#L3000008
High Pure RNA Isolation Kit	Roche	Cat# 11828665001
Deposited data
Original western blot images	This paper	Mendeley Data: https://doi.org/10.17632/7tg3tcyb4v.1
Experimental models: Cell lines
MDA-MB-231	ATCC	Cat#HTB-26, RRID:CVCL_0062
4T1	ATCC	Cat# CRL-2539, RRID: CVCL_0125
LentiX	ATCC	Cat#CRL-11270, RRID:CVCL_4401
CeLMP1	DSHB	RRID:CVCL_KR47
Experimental models: Organisms/strains
Mouse: NOD.Cg-Prkdcscid/J	The Jackson Laboratory	RRID:IMSR_JAX:001303
Oligonucleotides
Taqman probe for hmox1	Thermo Fisher Scientific	Cat# Hs01110250_m1
Taqman probe for actb	Thermo Fisher Scientific	Cat# Hs01060665_g1
siRNA targeting hmox1	Thermo Fisher Scientific	Cat# TRCN0000045250
siRNA targeting hmox1	Thermo Fisher Scientific	Cat#: TRCN0000045251
siRNA targeting aco1	Thermo Fisher Scientific	Cat# TRCN0000056553
siRNA targeting aco1	Thermo Fisher Scientific	Cat# TRCN0000056554
Recombinant DNA
pLV mCherry	Addgene	RRID:Addgene_36084
psPAX2	Addgene	RRID:Addgene_12260
pMD2.G	Addgene	RRID:Addgene_12259
Software and algorithms
Fiji/ImageJ 2	NIH	RRID:SCR_002285
Metamorph	Molecular Devices	RRID:SCR_002368
NIS-Elements	Nikon	RRID:SCR_014329
Prism 9	Graphpad	RRID:SCR_002798