Table 2.

Genotypes and dosing of AAV8-RLBP1

Cohort	ID#	Mutation (allele 1/2)	Volume injected (microliter)	Vector concentration (vg/microliter)	Vector dose (vg/eye)
C1	C1.A	677 T > A/700 C > T	150	3.3 x 107	5 x 109
	C1.B	677 T > A/700 C > T	150	3.3 x 107	5 x 109
	C1.C	700 C > T/700 C > T	150	3.3 x 107	5 x 109
C2	C2.A	700 C > T/700 C > T	300	3.3 x 107	1 x 1010
	C2.B	700 C > T/700 C > T	300	3.3 x 107	1 x 1010
	C2.C	700 C > T/700 C > T	300	3.3 x 107	1 x 1010
C3	C3.A	700 C > T/700 C > T	300	1 x 108	3 x 1010
	C3.B	700 C > T/700 C > T	300	1 x 108	3 x 1010
	C3.C	700 C > T/700 C > T	300	1 x 108	3 x 1010
C4	C4.A	700 C > T/700 C > T	300	3.3 x 108	1 x 1011
	C4.B	700 C > T/700 C > T	300	3.3 x 108	1 x 1011
	C4.C	700 C > T/700 C > T	300	3.3 x 108	1 x 1011

vg viral genomes.