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. 2024 Sep 10;14:21080. doi: 10.1038/s41598-024-71845-x

Table 5.

The prognostic factors for overall survival from the initial IPF diagnosis in the included studies.

References Risk factors HR (95% CI) P
Song et al. (2011) Age 1.017 (1.001–1.033) 0.032
FVC, % pred 0.987 (0.977–0.997) 0.009
DLco, % pred 0.985 (0.976–0.994) 0.001
Steroid with/without 1.552 (1.113–2.164) 0.01
cytotoxic agent occurrence of AE 2.592 (1.888–3.560) P < 0.001
Kakugawa et al. (2016) Cardiovascular diseases 2.37 (1.03–5.44) 0.042
GAP stage (≥ II) 3.63 (1.47–8.93) 0.005
SP-D, ng/mL 3.21 (1.21–8.48) 0.019

The FVC% value and the DLCO% value were obtained within one month after the first diagnosis.

FVC forced vital capacity, % pred % predicted, DLco diffusing capacity of the lung for carbon monoxide, AE acute exacerbation, GAP gender-age physiology, SP-D surfactant protein-D.