Table 2.

Longitudinal comparison of insulin, glucose, cortisol and growth hormone concentrations in Controls (n=77) and Patients with history of pituitary disease (n=62) within each group.

		0’ vs 30’	0’ vs 60’	0’ vs 90’	0’ vs 120’	0’ vs 150’	0’ vs 180’
INSULIN [µU/ml]	PATIENT	< 0.0001	< 0.0001	< 0.0001	0.2221	0.0346	<0.0001
	CONTROL	<0.0001	<0.0001	0.0006	0.0658	<0.0001	<0.0001
GLUCOSE [mg/dl]	PATIENT	< 0.0001	< 0.0001	0.0003	0.4502	0.0002	< 0.0001
	CONTROL	<0.0001	<0.0001	0.1703	0.0002	<0.0001	<0.0001
CORTISOL* [µg/dl]	PATIENT	0.1061	0.0369	0.0075	0.3373	0.0058	0.0002
	CONTROL	0.0427	<0.0001	<0.0001	0.0002	0.8298	0.0087
GROWTH HORMONE [ng/ml]	PATIENT	0.2398	0.5317	0.2633	0.0001	<0.0001	<0.0001
	CONTROL	0.7944	0.7944	0.1677	<0.0001	<0.0001	<0.0001

*Both in Patients and Controls cortisol concentrations at 30, 60, and 90 minutes were significantly lower than at 150 and 180 minutes, p<0.0001.

Statistically significant differences are highlighted in red, for precise numerical data see Table 1 .