Table 2.
N = 138 [blood tests not available for one patient] | N | DT 1 (N = 61) | DT < 1 (N = 77) | Chi-square/Fisher's Exact p value |
---|---|---|---|---|
Hemoglobin g/dl nadir | ||||
<8 | 34 | 22 (36%) | 12 (16%) | 0.010 |
8 | 104 | 39 (64%) | 65 (84%) | |
Absolute neutrophil count (ANC)/dl nadir | ||||
<1000 | 10 | 7 (11%) | 3 (4%) | 0.10 |
1000 | 128 | 54 (89%) | 74 (96%) | |
Platelet/dl nadir | ||||
<50,000 | 6 | 4 (3%) | 2 (3%) | 0.41 |
50,000 | 132 | 57 (93%) | 75 (93%) | |
Olaparib dose reduction | ||||
Yes | 30 | 14 (23%) | 16 (21%) | 0.96 |
No | 109 | 48 (77%) | 61 (79%) | |
Duration of olaparib therapy | ||||
Days (median, IQR) | 204 (127–319) | 103 (72–158) | <0.0001 |