Fig. 1.

mRNA expression analysis identifies chr8q genes associated with lethal prostate cancer. Shown are all chr8q genes (n = 400, normalized to units of SD for comparability) and odds ratios for lethal disease (metastases/death from prostate cancer), compared to nonlethal disease (no metastases for >8 y after diagnosis) in a whole-transcriptome profiling study among men with prostate cancer from the Health Professionals Follow-up Study and Physicians’ Health Study (n = 403, 1982 to 2019). Genes are sorted by odds ratio, and genes with odds ratio >2 as well as MYC are highlighted. Bars and estimates in parentheses are 95% CI.