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. 2024 Aug 18;9:100824. doi: 10.1016/j.crfs.2024.100824

Table 2.

Antioxidant activity of chemically modified EPS derivatives.

EPS producing Strain Tested dose of EPS Antioxidant capacity of various chemically modified derivatives of EPS
Degree of substitution (DS)
References
DPPH (%) Superoxide radical scavenging (%) Hydroxyl radical scavenging (%) FRAP Metal/chelation/Lipid peroxide inhibition (%) DS References
Antioxidant activity of sulfated EPS
Streptococcus thermophilus GST-6 1.0 mg/mL 18.29 for Sf;
9.26 for Um; 34.72 for AA
48.24 for Sf;
34.63 for Um;
45.01 for AA
59.22 for Sf; 36.47 for Um;
51.37 for AA
0.26 Zhang et al. (2016)
Streptococcus thermophilus ASCC 1275 1.0 mg/mL 10.07 for Sf;
7.40 for Um;
19.66 for Sf;
12.65 for Um;
12.63 for Sf;
7.85 for Um
0.31 Li and Shah (2014)
Pleurotus eryngii 1.0 mg/mL 14.55 for Sf;
7.71 for Um;
35.10 for Sf;
22.33 for Um;
23.44 for Sf;
21.81 for Um
0.69 Li and Shah (2014)
Lactobacillus helveticus MB2-1 4.0 mg/mL 59.5 for Sf; 38.0 for Um; 89.0 for vit C 60.5 for Sf; 50.0 for Um; 75 for vit. c 70.0 for Sf; 99 for Um; 55.5 for vit c Metal ion chelation
72 for Sf; 45.5 for Um; 99 for vit c
0.625 Xiao et al. (2020)
Lactobacillus plantarum BR2 2.0 mg/mL Approx. 64.75 for Sf; 61.0 for Um Approx. 55.0 for Sf; 35.0 for Um; 70.0 for vit c 41.0 for Sf; 15.0 for Um Soumya and Nampoothiri (2023)
Lactobacillus plantarum ZDY2013 2.0 mg/mL 20 for Sf;
2.5 for Um;
100 for Vit. c
Approx. 55 for Sf;
48 for Um;
90 for vit.c
Approx. 67 for Sf; 55 for Um; 90 for vit.c 0.29 Zhang et al. (2016)
Enterobacter cloacae Z0206 2.0 mg/ml Approx.85.06 for Sf;
30.0 for Um
80.66% for vit.c
Approx. 29.2 % for Sf; 12 for Um; 98 for vit.c 0.60 (Jin et al., 2011)
Enterobacter cloacae Z0206 2.0 mg/ml Approx. 89.80 for Sf;
30.0 for Um; 80.66% for vit.c
Approx. 31.5 for Sf, 12 for Um;
98 for vit.c
0.68 (Jin et al., 2011)
Antioxidant activity of acetylated EPS
Lactobacillus helveticus MB2-1 4 mg/mL 45.0 for Ac; 38.0 for Um; 89.0 for vit C 55.0 for Ac;
50.0 for Um; 75.0 for vit c
59.5 for Ac; 55.5 for Um; 99.0 for vit c Metal ion chelation
61.0 for Ac; 45.5 for Um; 99.0 for vit c
0.439 Xiao et al. (2020)
Lactobacillus plantarum BR2 2.0 mg/mL 73.81 for Ac; 61.0 for Um Approx. 40.0 for Ac; 35.0 for Um; 70.0 for vit c Reducing power
37.0 for Ac; 15.0 for Um
Soumya and Nampoothiri (2023)
Paenibacillus polymyxa EJS-3 1.0 mg/mL 77.8 for Ac; 40.4 for Um; 12.11 for Vit.c 80.26 for Ac; 68.55 for Um 0.53 Liu et al. (2012)
Lactobacillus plantarum 70810 4.0 mg/mL 49.5 for Ac; 28.18 for Um 58.48 for Ac; 30.46 for Um 0.41 (Wang et al. 2015)
Antioxidant activity of carboxymethylated EPS
Lactobacillus helveticus MB2-1 4.0 mg/mL 62.0 for Cm; 38.0 for Um; 89.0 for vit C 55.5 for Cm;
50.0 for Um; 75.0 for vit c
79.0 for Cm; 55.5 for Um; 99.0 for vit.c Metal ion chelation
68.0 for Cm; 45.5 for Um; 99.0 for vit c
0.526 Xiao et al. (2020)
Lactobacillus plantarum BR2 2.0 mg/mL 63.78 for Cm; 61.0 for Um Approx. 49.0 for Ac; 35.0 for Um; 70.0 for vit.c Reducing power
24.0 for Ac; 15.0 for Um
Soumya and Nampoothiri (2023)
Lactobacillus plantarum 70810 4.0 mg/mL 36.5 for Cm; 28.18 for Um 78.67 for Cm; 30.46 for Um 1.1 (Wang et al. 2015)
Leuconostoc spp 3.0 mg/mL 27.0 for Cm; 58 for Um ∼10.09 for Cm; 5.09 for Um 17.65 for Cm; 15.20 for Um 0.57 Li et al. (2021)
Leuconostoc spp 3.0 mg/mL ∼22.5 for Cm; 58.0 for Um ∼10.4 for Cm; 5.09 for Um 51.52 for Cm; 15.20 for Um 0.78 Li et al. (2021)
Leuconostoc spp 3.0 mg/mL 20.5 for Cm; 58.0 for Um ∼11.01 for Cm; 5.09 for Um 74.31 for Cm; 15.20 for Um 1.13 Li et al. (2021)
Leuconostoc spp 3.0 mg/mL 18.5 for Cm; 58.0 for Um ∼11.9 for Cm; 5.09 for Um 93.68 for Cm; 15.20 for Um 1.25 Li et al. (2021)
Antioxidant activity of phosphorylated EPS
Lactobacillus helveticus MB2-1 4 mg/mL 65.52 for Pr; 38.0 for Um; 89.0 for vit C 58.0 for Pr;
50.0 for Um; 75.0 for vit c
64.5 for Pr; 55.5 for Um; 99.0 for vit c Metal ion chelation
63.0 for Pr; 45.5 for Um; 99.0 for vit c
0.432 Xiao et al. (2020)
Lactobacillus plantarum 70810 4.0 mg/mL 54.95 for Cm; 28.18 for Um 31.5 for Cm; 30.46 for Um 0.08 (Wang et al. 2015)
Paenibacillus polymyxa EJS-3 1.0 mg/mL 47.3 for Pr; 40.4 for Um; 12.11 for vit. c 89.47 for Pr; 68.55 for Um 0.89 Liu et al. (2012)
Antioxidant activity of benzoylated EPS
Paenibacillus polymyxa EJS-3 1.0 mg/mL 89.8 for Bz; 40.4 for Um 72.37 for Bz; 68,55 for Um Liu et al. (2012)



Antioxidant activity of Selenized EPS
Bacillus licheniformis 4.0 mg/mL ∼39.3 for Sn; ∼39.7 for Um; ∼100 for vit. c ∼72.0 for Sn; ∼55.0 for Um;
‘∼100 for vit. C
∼79.5 for Sn; ∼73.4 Um;
∼100 for vit. C
Wang et al. (2023)

Where, Sf = sulfated EPS; Ac = acetylated EPS; Cm = carboxymethylated EPS; Pr = phosphorylated EPS, Bz = benzoylated EPS; Sn = selenized EPS; Um = unmodified; AA = Ascorbic acid (Positive control); vit.c = Vitamin C (+ve control).