. 2024 May 22;18:154–165. doi: 10.1016/j.aninu.2024.04.015

Table 2.

Effects of API supplementation on the growth performance of ETEC-challenged piglets.

Item	Treatments¹					SEM	P-value
Item	CON	ECON	EANT	E750API	E1500API	SEM	P₁²	P₂³
BW, kg
d 1	7.25	7.26	7.22	7.26	7.27	0.157	0.98	0.99
d 14	9.11	9.22	9.66	9.94	9.69	0.167	0.84	0.52
d 35	18.97	17.93	19.57	19.66	19.04	0.295	0.36	0.13
ADG, g/d
d 1–14	133.00	139.82^b	174.05^ab	191.58^a	172.65^ab	6.609	0.47	0.03
d 15–35	469.74	414.48^b	472.32^a	463.20^a	445.26^ab	8.026	0.11	0.04
ADFI, g/d
d 1–14	264.69	262.94	299.91	304.61	293.53	7.181	0.93	0.16
d 15–35	685.79	656.94	689.29	695.52	671.47	10.940	0.53	0.62
F/G, g/g
d 1–14	1.99	1.88^a	1.74^ab	1.60^b	1.73^ab	0.037	0.22	0.04
d 15–35	1.46	1.59∗∗^a	1.46^b	1.50^b	1.51^ab	0.015	<0.01	0.02
Diarrhea rate, %
d 1–14	16.67	14.29	12.50	11.31	13.69	0.981	0.57	0.74
d 15–35	20.00	47.08∗∗^a	35.83^b	35.00^b	39.17^b	1.421	<0.01	<0.01
Diarrhea index
d 1–14	0.59	0.53^a	0.45^ab	0.33^b	0.40^ab	0.026	0.51	0.04
d 15–35	0.49	1.29∗∗^a	0.83^b	0.92^b	0.87^b	0.057	<0.01	<0.01

API = artificial parasin I protein; ETEC = enterotoxigenic Escherichia coli; BW = body weight; ADG = average daily gain; ADFI = average daily feed intake; F/G = feed to gain ratio.

Mean and total SEM are listed in separate columns (n = 6).

CON = basal diet; ECON = basal diet + ETEC; EANT = basal diet + antibiotics + ETEC; E750API = basal diet + 750 mg/kg API + ETEC; E1500API = basal diet + 1500 mg/kg API + ETEC.

P₁ is the t-test P-value between CON and ECON group (∗P < 0.05, ∗∗P < 0.01).

P₂ is the ANOVA P-value among the ETEC-challenged groups (ECON vs. EANT vs. E750API vs. E1500API). Values with different lowercase letter superscripts within a row mean significant differences (P < 0.05).