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. 2024 May 22;18:154–165. doi: 10.1016/j.aninu.2024.04.015

Table 3.

Effects of API supplementation on serum biochemical indexes of ETEC-challenged piglets.

Item Treatments1
 SEM P-value
CON ECON EANT E750API E1500API P12 P23
TP, g/L 47.15 51.07∗ 50.47 50.97 50.47 0.726 0.03 0.99
ALB, g/L 26.48 28.97 28.86 29.29 28.30 0.523 0.19 0.94
ALT, U/L 35.50 48.37 55.97 47.89 53.58 3.294 0.24 0.80
AST, U/L 28.59 54.28∗∗a 35.64b 41.32ab 33.21b 2.665 <0.01 0.01
ALP, U/L 171.67 166.33 198.33 173.67 177.50 7.373 0.80 0.48
Urea, mmol/L 1.83 2.67 1.87 2.22 2.69 0.149 0.07 0.15

API = artificial parasin I protein; ETEC = enterotoxigenic Escherichia coli; TP = total protein; ALB = albumin; ALT = alanine transaminase; AST = aspartate transaminase; ALP = alkaline phosphatase. Mean and total SEM are listed in separate columns (n = 6).

1

CON = basal diet; ECON = basal diet + ETEC; EANT = basal diet + antibiotics + ETEC; E750API = basal diet + 750 mg/kg API + ETEC; E1500API = basal diet + 1500 mg/kg API + ETEC.

2

P1 is the t-test P-value between CON and ECON group (∗P < 0.05, ∗∗P < 0.01).

3

P2 is the ANOVA P-value among the ETEC-challenged groups (ECON vs. EANT vs. E750API vs. E1500API). Values with different lowercase letter superscripts within a row mean significant differences (P < 0.05).