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Examples of different degree of borrowing for data in Table 1
| Model | Probability(response rate in subgroup 5 > 30% | data) | |
|---|---|---|
| Scenario 1 | Scenario 2 | |
| Subgroup specific analysis | ||
| No borrowing Model: Beta-binomial |
.437 | .437 |
| Hierarchical model (Thall et al) | ||
| No Borrowing Mean of precision hyperprior .01 (Gamma(2,200)) |
.459 | .446 |
| Moderate borrowing Mean of precision hyperprior .1 (Gamma(2,20)) |
.453 | .382 |
| Strong borrowing Mean of precision hyperprior 1 (Gamma(2,2)) |
.464 | .160 |
