TABLE 1.
Genotype | Plaque phenotypea | NC accumulation (%)b |
---|---|---|
Wild type | lp | 100 |
CPΔ(71–75) | lp | 100 |
CPΔ(59–63) | lp | 85 |
CPΔ(39–43) | sp | <2 |
CPΔ(45–50) | vsp | <2 |
CPΔ(35–58) | vsp | <2 |
Determined by plaque assay in BHK cells 48 h posttransfection. lp, large plaque (3.0 to 3.5 mm); sp, small plaque (1.5 to 2.5 mm); vsp, very small plaque (<1.5 mm).
Determined at 12 h after electroporation of in vitro-transcribed RNA.