Table 2.

The death cases and ASDR of AML in 1990 and 2021, and its temporal trends from 1990 to 2021

	Death cases (95% CI)		Case change	ASDR (95% CI)		1990–2021 EAPCs (95% CI)
	1990	2021		1990	2021
Global	74,917 (58730–94714)	130,189 (113625–149385)	0.74% (0.39–1.03)	1.69 (1.36–2.08)	1.57 (1.37–1.8)	-0.15 (-0.2 to -0.1)
SDI
High SDI	24,617 (23487–25533)	47,188 (42904–49837)	0.92% (0.81–0.99)	2.33 (2.22–2.41)	2.31 (2.13–2.43)	0.05 (-0.03 to 0.13)
High-middle SDI	17,930 (13566–21775)	26,275 (22369–29543)	0.47% (0.2–0.79)	1.77 (1.35–2.15)	1.49 (1.26–1.69)	-0.36 (-0.44 to -0.27)
Middle SDI	19,742 (13362–28731)	31,807 (26106–39669)	0.61% (0.15–1.12)	1.42 (1.01-2)	1.24 (1.02–1.55)	-0.36 (-0.42 to -0.29)
Low-middle SDI	9555 (6251–15762)	18,801 (14556–25892)	0.97% (0.33–1.61)	1.09 (0.74–1.65)	1.18 (0.93–1.62)	0.35 (0.32–0.38)
Low SDI	2987 (1371–5392)	5971 (3645–7889)	1% (0.2–1.82)	0.83 (0.43–1.29)	0.81 (0.51–1.08)	-0.14 (-0.17 to -0.1)
Central Europe, eastern Europe, and central Asia
Central Asia	822 (708–956)	1080 (940–1269)	0.31% (0.12–0.57)	1.28 (1.12–1.48)	1.19 (1.04–1.39)	-0.28 (-0.36 to -0.2)
Central Europe	2446 (2287–2642)	3939 (3590–4275)	0.61% (0.48–0.75)	1.73 (1.61–1.86)	1.91 (1.74–2.08)	0.57 (0.48–0.65)
Eastern Europe	3586 (3306–3955)	3913 (3587–4265)	0.09% (-0.05 to 0.23)	1.44 (1.33–1.58)	1.28 (1.18–1.39)	-0.26 (-0.36 to -0.17)
High income region
High-income Asia Pacific	3861 (3626–4208)	7072 (6112–7719)	0.83% (0.58-1)	2.01 (1.87–2.2)	1.62 (1.42–1.75)	-0.58 (-0.7 to -0.47)
High-income North America	9677 (9127–9984)	18,371 (16623–19211)	0.9% (0.81–0.95)	2.8 (2.66–2.89)	2.85 (2.61–2.97)	0.13 (0.02–0.25)
Western Europe	11,122 (10603–11519)	22,485 (20222–23904)	1.02% (0.88–1.13)	2.08 (1.99–2.14)	2.43 (2.23–2.56)	0.6 (0.52–0.68)
Australasia	525 (490–561)	1519 (1358–1668)	1.89% (1.62–2.18)	2.29 (2.13–2.43)	2.82 (2.55–3.09)	0.4 (0.23–0.58)
Latin America and Caribbean
Andean Latin America	450 (326–637)	1037 (727–1306)	1.3% (0.55–2.05)	1.53 (1.15–2.09)	1.69 (1.19–2.13)	0.67 (0.59–0.75)
Central Latin America	1732 (1660–1809)	3792 (3378–4222)	1.19% (0.93–1.44)	1.31 (1.27–1.37)	1.51 (1.34–1.68)	0.39 (0.32–0.45)
Southern Latin America	861 (798–931)	1480 (1371–1609)	0.72% (0.55–0.9)	1.81 (1.67–1.96)	1.8 (1.67–1.96)	0.37 (0.22–0.52)
Tropical Latin America	2098 (2026–2175)	4589 (4273–4835)	1.19% (1.06–1.3)	1.78 (1.71–1.84)	1.85 (1.72–1.95)	0.3 (0.22–0.38)
North Africa and Middle East
North Africa and Middle East	5540 (3722–7974)	10,653 (7890–14414)	0.92% (0.51–1.45)	2.4 (1.68–3.3)	2.15 (1.6–2.94)	-0.28 (-0.34 to -0.23)
South Asia
South Asia	7145 (4461–11772)	14,565 (11115–20178)	1.04% (0.24–1.95)	0.87 (0.55–1.32)	0.92 (0.69–1.28)	0.23 (0.17–0.28)
Southeast Asia, east Asia, and Oceania
East Asia	15,429 (8480–24004)	16,505 (11574–22715)	0.07% (-0.35 to 0.82)	1.45 (0.82–2.19)	0.91 (0.64–1.27)	-1.41 (-1.6 to -1.23)
Oceania	94 (45–132)	195 (101–277)	1.07% (0.63–1.55)	2.09 (1.01–2.93)	1.91 (0.97–2.73)	-0.28 (-0.33 to -0.24)
Southeast Asia	6870 (4692–10215)	13,883 (9869–16854)	1.02% (0.46–1.54)	2.05 (1.38–2.9)	2.12 (1.53–2.58)	0.25 (0.18–0.32)
Sub-Saharan Africa
Eastern Sub-Saharan Africa	1007 (439–1805)	1858 (993–2669)	0.84% (-0.12 to 2)	0.7 (0.33–1.07)	0.64 (0.37–0.91)	-0.3 (-0.34 to -0.26)
Central Sub-Saharan Africa	249 (122–432)	532 (294–749)	1.14% (0.25–2.28)	0.72 (0.36–1.06)	0.65 (0.38–0.95)	-0.34 (-0.39 to -0.28)
Southern Sub-Saharan Africa	437 (279–612)	880 (602–1214)	1.01% (0.67–1.46)	1.28 (0.83–1.79)	1.39 (0.94–1.92)	0.23 (0.12–0.35)
Western Sub-Saharan Africa	475 (229–862)	1021 (570–1357)	1.15% (0.35–1.9)	0.32 (0.17–0.48)	0.31 (0.2–0.4)	0.06 (0.02–0.1)