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. 2024 Aug 20;15(9):e02043-24. doi: 10.1128/mbio.02043-24

Fig 4.

Microbiome analysis in WT and ASB3−/− mice with DSS treatment: Venn diagram of OTUs, alpha diversity, PCA of beta diversity, phylum-level relative abundance, and heatmap of differentially abundant genera.

ASB3−/− mice appear to have altered fecal microbiota. (a) Venn diagram depicting the number of microbiota at the bacterial taxa (phylum, class, order, and family) in the feces collected from WT and ASB3−/− mice at day 0 or day 6 of DSS-induced colitis. (b) Analysis of the bacterial diversity of fecal microorganisms from DSS-induced colitis in WT and ASB3−/− mice before and after. (c) Principal coordinate analysis (PCoA) of the weighted UniFrac distances of the fecal microbiota of WT and ASB3−/− mice pre- and post-DSS challenge (n = 6 per group). (d) The relative abundance of microbial symbiont diversity was analyzed at the phylum level. (e) The relative abundance of microbial symbiont diversity was analyzed at the genus level.